IBM support notes that SmartSuite will not operate on 64-bit Vista (or later)
There are no plans to implement official support for SmartSuite on Win7
On platforms other than XP (i.e. Server 2003, Vista, Server 2008, etc.), the client/server runtime environment that renders the Windows GUI can get bogged down when drawing poorly designed forms. Generally, these apparent "Vista bugs" can be fixed by redesigning the form so that fields are not crammed together.